Cu(II) and Zn(II) complexes incorporated with active analogue fragments molecule of the aristolochic acid: Crystal structure and biological activity

Journal of Molecular Structure(2022)

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摘要
•On the base of aristolochic acid analogue, new copper and zinc complexes were synthesized.•Complexes behaved strong binding affinities in DNA interaction.•Complexes possessed a superior level of toxicity to inhibit HepG2, SKOV-3, cell lines.
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关键词
Cu(ii)/Zn(ii) complexes,Analogs,Hirshfeld surface analysis,Crystal structures,Anticancer activity
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