Photoinduced bleaching in an efficient singlet oxygen photosensitizing protein: Identifying a culprit in the flavin-binding LOV-based protein SOPP3

Ditte J. Mogensen,Michael Etzerodt,Peter R. Ogilby

Journal of Photochemistry and Photobiology A: Chemistry（2022）

引用 5|浏览16

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摘要

•Bleaching of FMN in SOPP3 depends on electron transfer with surrounding molecules.•Amino acids in SOPP3 mediate the bleaching reaction of bound FMN.•Despite FMN bleaching, SOPP3 is still be a viable intracellular optogenetic actuator.

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关键词

Reactive oxygen species (ROS),Singlet oxygen,Optogenetic photosensitizers

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