Association of CYP2C19*2/3 gene polymorphism with lung cancer in Moroccan population

Hind Berradi,Houda Kaanane,Hind Hassani Idrissi, Nadia Elkadmiri,Nadia Benchakroun,Abdellatif Benider,El Hassan Izaabel,Sellama Nadifi

Gene Reports（2021）

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摘要

•The CYP2C19 gene code for one of the main enzymes involved in the metabolism of xenobiotics•CYP2C19*2/*3 polymorphisms are responsible of reduction of enzyme activity.•CYP2C19*2/*3 polymorphisms increased lung cancer risk in Moroccan population.•CYP2C19*3 which coexisted with smoking increases lung cancer risk even more.

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关键词

CYP450,EM,EET,IM,LC,PM

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