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Confirmation of endotypes based on levels of eosinophil, mast cell and basophil microparticles in nasal lavage fluids in chronic rhinosinusitis with nasal polyps using two Northwestern Memorial Hospital cohorts

Toru Takahashi,Lydia Suh,Roderick Carter,Kris Erickson,Julia Huang,James Norton,Atsushi Kato,Sergejs Berdnikovs,Whitney Stevens,Anju Peters,Leslie Grammer,Stephanie Shintani Smith,Bruce Tan,David Conley,Kevin Welch,Robert Kern,Robert Schleimer

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY（2022）

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Abstract
Microparticles (MPs) are extracellular vesicles that are released by shedding from plasma membrane of activated cells and new biomarkers to evaluate status of cell activation. MP profilings of activated eosinophils, mast cells and basophils in nasal mucosa in chronic rhinosinusitis with nasal polyps (CRSwNP) remain unclear.
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nasal polyps,nasal lavage fluids,chronic rhinosinusitis,eosinophil,mast cell
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