The Influence of Modafini on the Visual Function of 16-hour Simulation Flight

To observe the effect of modafinil on the visual function of 16-h flight. Methods 5 male healthy subjects were double-blind: placebo group (n = 5) and modafinil group (n = 5), Autologous control. Carry out 16 h (h) continuous simulated long flight test across day and night. First, the visual function is detected before flight, In pairs, at the same time, First phase 8 h at 15:30, After 200 mg, of modafenib or placebo 00:00 Completion of phase 2 h 8 flights, After the flight, the visual function was detected again and the state changes of far and near vision were compared before and after the flight. Results Compared with placebo, the use of modafinil had no significant effect on far and near vision, but increased the long vision of both eyes during flight. Conclusion Routine single dose of modafinil has no significant adverse effect on visual function and can reduce human fatigue perception.