Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy

Ziyan S. Ahmed,Rinsha P. Sherin,Tatiana L. Fonseca,Thanh D. Hoang,Mohamed K. M. Shakir

CLINICAL CASE REPORTS（2022）

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摘要

We report a 54-year-old man with treatment-resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.

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关键词

depression, hypothyroidism, polymorphism, T3

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