Synthesis of a versatile Schiff base 4-((2-hydroxy-3,5-diiodobenzylidene)amino) benzenesulfonamide from 3,5-diiodosalicylaldehyde and sulfanilamide, structure, electronic properties, biological activity prediction and experimental antimicrobial properties

N. Elangovan,Bhavya Gangadharappa,Renjith Thomas,Ahmad Irfan

Journal of Molecular Structure（2022）

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摘要

•Synthesis of a new Schiff's base 3,5-diiodosalicylaldehyde and sulfanilamide.•NMR, IR and UV studies and frequency assignment.•Compound is antimicrobial and antifungal.•Excellent docking score against Staphylococcal Peroxidase Inhibitor.

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关键词

Schiff base,Dft,3,5-diiodosalicylaldehyde,Drug likeness,Antimicrobial,Docking

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