State-of-the-art nanotechnologies for the detection, recovery, analysis and elimination of liquid biopsy components in cancer

Nano Today(2022)

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摘要
•Potential blood-based biosources in cancer liquid biopsy were introduced.•We reviewed nanoparticle-labeled with targeting-moieties, nanostructured substrates and nanobiosensors in liquid biopsy.•The mechanisms and methods of using functional nanoparticles to capture and recover CTCs were summarized.•Nanotechnology-mediated downstream analysis and elimination of CTCs were also discussed.•We offered an outlook on the challenges and suggestions for nanotechnology-based cancer liquid biopsy.
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关键词
Liquid biopsy,Circulating tumor cells,Extracellular vesicles,Circulating tumor DNA,Nanotechnology,Nanoparticles,Nanostructured substrates
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