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Linking sporadic hospital clusters during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 delta variant: The utility of whole-genome sequencing

Liang En Wee,Karrie Kwan-Ki Ko,Edwin Philip Conceicao,Jean Xiang-Ying Sim,Nurdyana Abdul Rahman,Shireen Yan-Ling Tan,Delphine Yan-Hong Cao, Kenneth Xing-Long Chan,May Kyawt Aung,Myat Oo Aung,Yang Yong,Shalvi Arora,Molly Kue Bien How,Kwee Yuen Tan,Lai Chee Lee,Thuan Tong Tan,Limin Wijaya,James Heng Chiak Sim,Chayaporn Suphavilai,Indumathi Venkatachalam,Moi Lin Ling

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY（2023）

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Abstract
Sporadic clusters of healthcare-associated coronavirus disease 2019 (COVID-19) occurred despite intense rostered routine surveillance and a highly vaccinated healthcare worker (HCW) population, during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 delta (delta) variant. Genomic analysis facilitated timely cluster detection and uncovered additional linkages via HCWs moving between clinical areas and among HCWs sharing a common lunch area, enabling early intervention.
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