Isolation and characterization of bioactive phenolic compounds from Cinnamomum camphora barks
HOLZFORSCHUNG(2022)
摘要
Two new phenolic rhamnosides (1-2) and 12 known phenolic compounds (3-14) were isolated from the ethanolic extract of Cinnamomum camphora barks by repeated column chromatography. The structures of all isolated compounds were identified by comprehensive spectroscopic data analysis such as high-resolution electrospray ionization mass spectra, nuclear magnetic resonance, optical rotatory dispersion and chemical method. In vitro assay revealed that compound 8 showed strong inhibitory activity against tyrosinase, and compounds 1, 3-7, 8-9, 13 showed obvious acetylcholinesterase inhibitory activity.
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关键词
acetylcholinesterase, Cinnamomum camphora, rhamnoside, tyrosinase
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