Sub-100 nm and ultra-thin hollow Gd2O3 nanospheres for effective magnetic resonance imaging T1 contrast agent

Journal of Alloys and Compounds(2022)

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摘要
•Ultra-thin hollow Gd2O3 nanospheres with maximized surface gadolinium atoms to improve the MRI T1 relaxivity.•Tunable diameter of hollow Gd2O3 nanospheres to facilitate the design of clearance path and blood circulation.•Realize the relationship between shell thickness of hollow Gd2O3 nanospheres and MRI T1 relaxivity.
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关键词
Relaxivity,Toxicity,Shell thickness,Blood circulation,Template
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