The Association between the Location and Extent of Pulmonary Embolism and Pulmonary Artery Pressure in Elderly Patients with Gastric Cancer

Geng Ma,Pei Pei Li,Jin Rong Wang, Zhao Bo Cui, Na Qi

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES(2021)

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摘要
To explore the relationship between pulmonary artery pressure and embolization area and embolization site in elderly patients with gastric cancer and pulmonary embolism. 118 patients with gastric cancer and acute pulmonary embolism who were hospitalized in Harrison International Peace Hospital from August 2017 to August 2020 were selected as the research objects. Doppler echocardiography was used to assess the pulmonary artery pressure of the patients and the patients were divided into two groups: pulmonary hypertension and non-hypertension groups. The differences in general information, blood gas analysis, D-dimer, coagulation indexes, typical clinical symptoms and the location and area of pulmonary embolism between the two groups were compared. The relationship between different levels of pulmonary artery pressure and the area and location of pulmonary embolism were investigated. The age and heart rate of patients in the pulmonary hypertension group were significantly higher than those in the non-high pressure group and the systolic blood pressure was significantly lower than that in the non-high pressure group; the level of the D-dimer in the high pressure group was significantly higher than that of the non-high pressure group; the levels of partial pressure of oxygen and partial pressure of carbon dioxide in the high pressure group were significantly lower than non-high pressure group; the incidence of syncope and hemoptysis in the high pressure group was significantly higher than that of the non-high pressure group; the proportion of large area embolism and multilateral embolism in the high pressure group was significantly higher than that of non-high pressure group; the severity of pulmonary artery pressure was severe or moderate; severe-large area embolism and multilateral embolism account for a larger proportion. Patients with pulmonary hypertension are more likely to have large area embolism and multilateral embolism and patients with moderate and severe pulmonary hypertension are more likely to have large area embolism and multilateral embolism, which may indicate a more serious condition and a poor prognosis.
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关键词
Pulmonary embolism, gastric cancer, pulmonary artery pressure, partial pressure of oxygen, partial pressure of carbon dioxide
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