Sleep quality, purpose in life, and health related quality of life among people living with HIV in Nigeria

Background: Sleep has been linked to multiple health outcomes. We aim to determine the relationship between sleep quality, purpose in life, and HRQoL among PLHIV. Methods: We conducted a cross-sectional study among 401 PLHIV in the HIV clinic using a structured questionnaire that included their demographics, Pittsburgh Sleep Quality Index (PSQI), Ryff's Scales of Psychological Well-Being, and Veterans RAND 12-item Health Survey (VR-12). Results: Ninety-two [22.9%] were classified as having poor sleep quality. Poor sleepers had significantly lower scores in the physical component [48.0 (9.5) vs. 51.2 (7.1), p = .014] and mental component 44.7 (10.5) vs. 52.1 (9.8), p < .001 in HRQoL as compared to good sleepers. Purpose in life moderates the effect of sleep quality on the physical component of HRQoL, p(interaction) = .003. Conclusion: Assessing sleep quality and purpose in life routinely among HIV-infected patients may impact the overall wellbeing of PLHIV.