An Efficacious Protocol for the Reduction of Benzothiazole Using Mg/MeOH and Their Antinemic Activity against Meloidogyne incognita

A novel series of substituted benzothiazole derivatives were synthesized by reacting with various aryl aldehydes and magnesium turnings/dry MeOH as reducing agent. These compounds were characterized with various spectral techniques. The resultant compounds were screened for their antinemic activity against root knot nematode, Meloidogyne incognita by egg hatching and mortality test. All the tested compounds showed vital efficacy as antinemic agents against M. incognita . The results indicated that synthesized benzothiazole derivatives exhibited significant antinemic activity, of which synthesized compound 2-(4-chlorophenyl)-2,3-dihydrobenzothiazole showed the best nematicidal activity as compared to other benzothiazole derivatives.