A blueprint for glow tag engineering

NATURE REVIEWS CHEMISTRY（2021）

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摘要

In two seminal papers published 25 years ago, Phillips and Remington reported the structure of the green fluorescent protein (GFP). These studies provided a blueprint for the rational engineering of GFP, catalysing efforts that produced a large and growing collection of fluorescent proteins and indicators of cellular activity.

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关键词

Protein design,X-ray crystallography,Chemistry/Food Science,general,Analytical Chemistry,Organic Chemistry,Physical Chemistry,Inorganic Chemistry,Biochemistry

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