Synthesis of diaryl urea derivatives and evaluation of their antiproliferative activities in colon adenocarcinoma

Muhammed Gomec,Fatih Yulak,Hayreddin Gezegen,Mustafa Ozkaraca,Koray Sayin,Hilmi Ataseven

Journal of Molecular Structure（2022）

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摘要

•Diaryl urea derivatives were designed and synthesized.•Computational analyses were performed.•Their antiproliferative activity and anticancer properties were examined as experimentally.•Molecular docking were done against colon cancer.

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关键词

Synthesis,Anticancer,Colon cancer,Diaryl urea,In silico

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