Temperature shift and feeding strategies for improving l-lactic acid production by Lactiplantibacillus plantarum in batch and fed-batch cultures

Process Biochemistry(2022)

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摘要
•Temperature shift from lower temperature in an early stage improves LAC formation.•The highest PLAC is obtained in 25–35 °C shifted at the early exponential growth (3 h).•PLAC is enhanced by feeding 20 g/L glucose at 9 h using exponent of 0.025 for feed rate.•The combined temperature shift and off-line feeding strategy improves PLAC.
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关键词
Temperature shift,Feeding strategies,l-lactic acid,Lactiplantibacillus plantarum,Fed-batch culture
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