THE IMPACT OF ETHNICITY ON OUTCOMES IN AUTOLOGOUS OOCYTE CRYOPRESERVATION/THAW CYCLES.

To compare live birth (LB) and cycle characteristics by self-reported ethnicity in IVF cycles using autologous vitrified/thawed oocytes. We retrospectively identified autologous IVF cycles using vitrified oocytes from 2009 to 2020 in women who self-identified as Asian, Black, Hispanic, or White. Those without ethnicities reported were excluded. Ovarian stimulation, oocyte vitrification/thaw, IVF, ICSI, embryo culture/transfer/embryo vitrification were performed using published protocols. Primary outcome was LB per embryo transfer (ET) cycle. Statistical comparisons were performed using ANOVA, Chi-square or Proportion tests. Post-hoc analyses were performed for group comparisons where appropriate. In 523 individual oocyte thaw cycles, all ethnicities had similar numbers of MIIs and numbers of total and cryopreserved embryos per thaw cycle. Average age at time of oocyte cryopreservation was highest in Black women (p=0.024). BMI was statistically lower in Asian women and higher in Black women compared to all other groups (p<0.001). LB per all ETs as well as fresh and frozen ETs individually were not statistically different between the four groups. In IVF cycles using autologous vitrified/thawed oocytes, LB outcomes were similar across ethnicities, though numbers in ethnic minority groups were low. As more women return to thaw oocytes, continued collection of outcomes may further our understanding of ethnic disparities in IVF after autologous oocyte cryopreservation.