Noninvasive Capsulotomy for Refractory Depression by Frameless Stereotactic Radiosurgery

Mohamed H Khattab,Alexander D Sherry,Sean P Devan,Guozhen Luo,Basil H Chaballout, Samuel Jean-Baptiste,Junzhong Xu,Sarah Bick,William M Petrie,Anthony J Cmelak

International Journal of Radiation Oncology*Biology*Physics（2022）

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摘要

In 3 patients with refractory depression, radiosurgical capsulotomy significantly reduced the burden of depression. Functional connectome reorganization offers neurobiological evidence to support further investigations of the role of radiosurgery in depression.

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