Tumor-associated macrophages regulate the function of cytotoxic T lymphocyte through PD-1/PD-L1 pathway in multiple myeloma.
Cancer medicine（2022）
Abstract
Our study shows that TAMs were increased in MM patients which can inhibit the function of cytotoxic T lymphocyte (CTL) through the PD-1/ PD-L1 signaling pathway and participate in the occurrence of immune escape of myeloma cells.
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Key words
CD8 + T cells,CSF1R,PD-1/PD-L1,TAMs,multiple myeloma
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