Assessment of the effects of organic vs. inorganic arsenic and mercury in Caenorhabditis elegans

Jessica Camacho,Aline de Conti,Igor P. Pogribny,Robert L. Sprando,Piper Reid Hunt

Current Research in Toxicology（2022）

引用 6|浏览5

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摘要

•Similar developmental delays and oxidative stress with 20x DMA relative to NaAsO2.•Dissimilar gene expression and locomotion with organic vs. inorganic mercury.•Dissimilar unfolded protein responses for organic vs. inorganic arsenic and mercury.•Across phyla, methylation has opposite effects on arsenic vs. mercury toxicity.

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关键词

DMA,DEGs,ER,EXT,GO,HgCl2,iAs,L1,LD50,LOEL,meHgCl,NaAsO2,NOEL,OxStrR,TOF,UPR

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