Immunohistochemical expression of transcription factors PAX5, OCT2, BCL6 and transcription regulator P53 in Non-Hodgkin lymphomas: A diagnostic cross-sectional study
Annals of Medicine and Surgery(2022)
Abstract
•Transcription factors are essential for the differentiation of B-cells.•PAX5 and OCT2 provide more accuracy in the diagnosis of lymphomas.•BCL6 expression reflects its role in germinal center formation.•P53 expression is higher in aggressive subtypes.
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Key words
Non-Hodgkin Lymphoma,Transcription factors,Transcription regulators,Immunohistochemistry,Classification
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