Autophagy: A New Mechanism for Esketamine as a Depression Therapeutic

Guanghao Jiang,Yibo Wang,Qingzhen Liu,Tingting Gu,Suting Liu,Anqi Yin,Lidong Zhang

Neuroscience（2022）

引用 11|浏览8

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摘要

ESK reverses LPS-induced depression-like behavior by activating mTOR to inhibit autophagic impairments, while the mTOR inhibitor rapamycin opposes ESK.

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关键词

3-MA,ATGs,EPM,ESK,FST,LPS,MDD,TST

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