Late onset Wilson Disease with normal neuro-psychiatric status: A case report

ANNALS OF MEDICINE AND SURGERY(2022)

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Abstract
Introduction: Late onset Wilson disease (WD) is a rare form of WD. WD has variability of clinical presentations from acute liver failure to chronic liver disease (CLD). The hepatic and neurological variants of WD have wider variations.Case presentation: A 55-year-old female, known case of CLD, presenting with generalized body swelling and abdominal pain, was diagnosed with late onset WD with normal neuro-psychiatric status. She was treated with zinc and considered for liver transplantation. Clinical discussion: Late onset WD is itself a rare form of WD. Within it, neurological manifestations are common in late onset WD, which was quite opposite as compared to our case. Similarly, diagnostic delay has been a concern in late onset WD with CLD as with our case. Conclusions: In spite of being uncommon in later age, WD and its different variations like with normal neuropsychiatric status should be considered as an etiology in cases of unexplained liver diseases.
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Key words
Wilson disease,Chronic liver disease,Kayser-Fleischer ring,Leipzig scoring
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