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Evaluation of a tryptase depletion index for better pathologic identification of mast cell activation syndrome.

Tomasz Zienkiewicz,Jürgen Homann,Martin Mücke,Holger Seidel,Hans-Jörg Hertfelder,Leonard B Weinstock,Lawrence B Afrin,Gerhard J Molderings

Zeitschrift fur Gastroenterologie（2023）

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Abstract
The TDI may discriminate between MCAS patients vs. controls. If this preliminary work can be independently confirmed, the TDI may become a useful additional minor diagnostic criterion for MCAS.
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Key words
mast cell activation syndrome,mast cell density,mast cell activation,diagnostic criteria,CD117-antibody staining,tryptase-antibody staining,tryptase depletion index
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