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Evidence for a Role of CCR6+ T Cells in Chronic Thromboembolic Pulmonary Hypertension.

Denise van Uden,Thomas Koudstaal,Jennifer A C van Hulst,Thierry P P van den Bosch,Madelief Vink,Ingrid M Bergen,Karishma A Lila,Annemien E van den Bosch,Paul Bresser,Mirjam Kool,Jan H von der Thüsen,Rudi W Hendriks,Karin A Boomars

Frontiers in immunology（2022）

Cited 2|Views16
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Abstract
The observed increase of CCR6 T cells and modulation of the IFNγ and IL-17 production capacity of circulating CD4 T cells at diagnosis and 1-year follow-up - together with the presence of CCR6 T cells in vascular lesions - support the involvement of the Th17-associated CCR6 T cell subset in CTEPH.
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Key words
CCR6,CTLA4 ,T cell,chronic thromboembolic pulmonary hypertension,cytokine,immunology
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