Possibilities of quadripolar radiofrequency therapy as a method of rehabilitation after surgery for pelvic organ prolapse

Ju. E. Dobrokhotova,I. R. Grishin, Irina Iu. Il’ina,E.N. Kareva, Sofia A. Zalesskaya, T. S.K. Nagieva, Vladimir I. Komagorov,Aleksandr I. Grishin,Polina A. Shadrova, Amina Iu. Azimova

Гинекология(2021)

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摘要
Background. This article is devoted to a topical topic in gynecology genital prolapse and methods of preventing recurrence in the postoperative period. Despite the surgery in the field of correction of genital prolapse, up to 13% of patients require repeated surgical treatment of this pathology in the postoperative period. Aim. At present, a unified algorithm for rehabilitation after operations to eliminate this pathology has not yet been developed. We proposed a technique for using quadripolar radiofrequency therapy in patients operated on for pelvic organ prolapse in the postoperative period in order to improve the rehabilitation period. Materials and methods. To achieve our goals, histological material was collected from 60 patients with pelvic organ prolapse before and after surgical treatment to assess the strength of collagenogenesis and reparative processes in the connective tissue of the vagina based on changes in the expression of the RNA matrix of collagen types I and III, genes encoding vascular endothelial growth factor VEGF-A, transforming growth factor TGF-B1 and decorin by polymerase chain reaction. The FSFI-19 questionnaire was used to analyze the quality of the patients' sexual life. We also calculated the vagina health index of patients suffering from this disease. Results. In the course of the study, it was revealed that when using this method, complete re-epithelization of tissues occurs by 90 days after the operation, metabolic and trophic processes in the tissues of the urogenital tract intensify, and an increased degree of patient satisfaction with the quality of sexual life. Conclusion. All the results obtained confirmed the therapeutic effect of radiofrequency therapy in the postoperative period, which makes it possible to use the technique as a rehabilitation program after surgical treatment for genital prolapse.
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关键词
genital prolapse,recurrence of genital prolapse,rehabilitation period,dynamic quadripolar radiofrequency therapy (dqrftm),collagenogenesis,neovascularization,vascular endothelial growth factor,transforming growth factor,decorin
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