POS-409 IDENTIFICATION OF IMPORTANT PATHOLOGICAL mRNA and microRNA TRANSCRIPTS INVOLVED IN WILMS TUMOR AND RHABDOID TUMOR OF THE KIDNEY USING ASSOCIATION RULE MINING
Kidney International Reports(2022)
Abstract
Wilms tumor (WT) and rhabdoid tumor of the kidney (RT) are respectively the most and less common types of pediatric kidney tumors. Due to the presence of overlapping histologic patterns and similar cell types across these tumors, their differential diagnosis solely based on histologic study can be challenging. To this end, this study aimed to apply machine learning and deep learning algorithms to identify the most important mRNAs and microRNAs panels that can be involved in the pathogenesis of the WT and RT.
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Key words
Wilms Tumor
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