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Glial cell-Derived, but Not Neuron-Derived, Extracellular Vesicles May Serve as Novel Biomarkers of Acute Sport-Related Concussion.

Meghan Rath,Jacqueline Sayoc,Karlee Burns,Jane McDevitt,Xiaoxuan Fan,Ryan Tierney,Jingwei Wu,Joon Y Park

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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Abstract
. Glial cell-derived EV concentrations were significantly higher among athletes with acute SRC compared to controls, while neuron-derived EVs did not differ. Our results suggest that analysis of brain cell-specific EVs may shed new light on a way to leverage EV-based biomarker discovery for SRC.
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Key words
extracellular vesicles,novel biomarkers,cell‐derived
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