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Gentiopicroside ameliorates acute inflammatory kidney injury in a mouse model induced by LPS through hampering NF-κB, AP-1 and IRF3 pathways.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology(2022)

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摘要
This study clearly revealed that gentiopicroside exerted a dose dependent anti-inflammatory and kidney protective effects in LPS-induced acute kidney injury. The observed effects were resulted through hampering of NF-κB, AP-1 and IRF3 pathways.
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inflammatory kidney injury,irf3 pathways
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