Endothelial-specific nanodelivery of Rho kinase inhibitors: Targeting tumor angiogenesis and metastasis.

Behnaz Lahooti,Racheal Akwii,George Mattheolabakis,Constantinos M Mikelis

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

We have successfully developed Fasudil-encapsulated, CD31-targeting liposomes. Future studies will be directed to study the formulation's effect on endothelial physiology in vitro and in vivo, tumor growth, angiogenesis, and metastasis.

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