FXR1 Decreases Blood Pressure by Regulating Vascular Contractility.

Amanda St Paul,Kyle Preston,Cali Corbett,Tani Leigh,Sheri Kelemen,Rachael Okune,Satoru Eguchi,Dale Haines,Michael Autieri

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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摘要

These data are the first to suggest FXR1 regulates blood pressure and vascular contractility potentially by two mechanisms: mRNA stability and functional activity by protein-protein interactions. The findings support FXR1 activity may represent a target for therapeutic invention to regulate blood pressure.

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blood pressure,vascular contractility

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