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Sleep Apnea and Kidney Disease: The Role of Hypoxia and Lysyl Oxidase.

Ann Thomas,Nishka R Jakkidi,Shiyu Li,Kit-Yan Cheng,Michelle Gumz,Muna T Canales,Rajesh Mohandas

FASEB journal : official publication of the Federation of American Societies for Experimental Biology（2022）

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Abstract
Our results showed that HIF-1α and LOX expression in PBMC was decreased in patients with CKD regardless of if they had SA or not. The mechanisms underlying these observations, the functional significance, and if these changes are representative of tissue LOX expression needs further studies.
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Key words
hypoxia,kidney disease
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