Central nervous system 5-HT plays a role in ventilatory and arousal responses to hypoxia and hypercapnia in spinal cord injured mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology(2022)
Abstract
The ventilatory, arousal and GG response to hypercapnia and hypoxia is greater in Tph2 compared to Tph2 mice following SCI. Our results suggest that deficiencies in serotonin have a role in regulating respiratory and arousal responses to hypercapnia and hypoxia following SCI.
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Key words
hypoxia,spinal cord,hypercapnia,ventilatory,arousal responses
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