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Central nervous system 5-HT plays a role in ventilatory and arousal responses to hypoxia and hypercapnia in spinal cord injured mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology(2022)

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Abstract
The ventilatory, arousal and GG response to hypercapnia and hypoxia is greater in Tph2 compared to Tph2 mice following SCI. Our results suggest that deficiencies in serotonin have a role in regulating respiratory and arousal responses to hypercapnia and hypoxia following SCI.
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Key words
hypoxia,spinal cord,hypercapnia,ventilatory,arousal responses
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