SARS-CoV-2 Delta-Omicron Recombinant Viruses, United States

Kristine A Lacek,Benjamin L Rambo-Martin,Dhwani Batra,Xiao-Yu Zheng,Norman Hassell, Hitoshi Sakaguchi,Thomas Peacock,Natalie Groves,Matthew Keller,Malania M Wilson,Mili Sheth,Morgan L Davis, Mark Borroughs,Jonathan Gerhart,Samuel S Shepard,Peter W Cook,Justin Lee, David E Wentworth,John R Barnes,Rebecca Kondor,Clinton R Paden

EMERGING INFECTIOUS DISEASES（2022）

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摘要

To detect new and changing SARS-CoV-2 variants, we investigated candidate Delta-Omicron recombinant genomes from Centers for Disease Control and Prevention national genomic surveillance. Laboratory and bioinformatic investigations identified and validated 9 genetically related SARS-CoV-2 viruses with a hybrid Delta-Omicron spike protein.

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关键词

2019 novel coronavirus disease,COVID-19,Delta,Omicron,SARS-CoV-2,United States,bioinformatics,coronavirus disease,next-generation sequencing,recombination,respiratory infections,severe acute respiratory syndrome coronavirus 2,viruses,zoonoses

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