Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse.

Wanjing Huang,Qiang Xu,Feng Liu,Jing Su,Dongchang Xiao,Lei Tang,Zhao-Zhe Hao,Ruifeng Liu,Kangjian Xiang,Yalan Bi,Zhichao Miao,Xialin Liu,Yizhi Liu,Sheng Liu

Investigative ophthalmology & visual science（2022）

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摘要

Ectopic expression occurs in the retina but not in the substantia nigra pars compacta in the DAT-tdTomato mouse, and fluorescently labeled cells in the retina are TPBG-expressing GABAergic ACs. This type of transgenic mice has been proved as an ideal tool to achieve efficient labeling of a distinct subset of ACs that selectively express Tpbg.

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关键词

DAT-Cre, GABAergic amacrine cells, patch-seq, TPBG, TH

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