Photoinduced Three-Component Difluoroalkylation of Quinoxalinones with Alkenes via Difluoroiodane(III) Reagents

An environmentally friendly strategy for the photocatalyzed three-component reaction between quinoxalinones, alkenes, and hypervalent iodine­(III) reagents is disclosed. The new designed difluoroiodane­(III) reagent shows excellent reactivity, providing a wide range of difluoroalkyl-substituted quinoxaline-2­(1H)-ones in moderate to excellent yields under mild conditions. Experimental studies demonstrated that a difluoroalkyl radical intermediate was involved in this reaction.