PIK3CA, KI67, Estrogen and Progesterone Receptors Expression Pattern in HER2 Positive Breast Cancers

Female breast cancer is currently the leading cause of global cancer incidence, with an estimated 2.3 million new cases, representing 11.7% of all cancer cases [1]. It is the fifth leading cause of cancer mortality worldwide, with 685,000 deaths [1]. Among women, breast cancer accounts for 1 in 4 cancer cases and for 1 in 6 cancer deaths, ranking first for incidence in the vast majority of countries and for mortality in 110 countries [1]. Nigeria is the most populous country in Africa, with approximately 20% of the continent’s population and slightly more than half that of West Africa [2, 3]. According to Global Cancer Statistics Abstract