Mutant SF 3 B 1 promotes AKT and NFk B driven mammary tumorigenesis

1Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA 2CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, 3China National Center for Bioinformation, Beijing 100101, China 4Program for Mathematical Genomics, 5Departments of Systems Biology and Biomedical Informatics, Columbia University, New York, NY, USA 6Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA 7Antitumor Assessment Core and Molecular Pharmacology Department, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA 8Leukemia Service, Dept. of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA 9Weill-Cornell Medicine, New York, NY, USA 10Breast Medicine Service, Dept. of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA