Distinctive therapeutic effects of non-euphorigenic hemp extracts in osteoarthritis

Purpose: Osteoarthritis (OA) is the leading cause of disability in older adults and involves complex interactions of local and systemic factors clinically characterized as joint pain and loss of function. Current treatment offers symptoms management and joint replacement surgery, with no disease modifying agents available. Hemp products, specifically cannabinoids, are widely used by the public to control pain and inflammation in many diseases; but there is not scientific evidence demonstrating their efficacy in OA.