The effect of COVID-19 on transplant function and development of CLAD in lung transplant patients: A multicenter experience

Elizabeth Roosma,Johanna P van Gemert,Auke E S de Zwart,Coretta C van Leer-Buter,Merel E Hellemons, Elize M Berg,Bart Luijk,Rogier A S Hoek,Diana A van Kessel,Onno W Akkerman,Huib A M Kerstjens,Erik A M Verschuuren,C Tji Gan

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2022）

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摘要

In LTx patients COVID-19 results in high mortality in hospitalized patients. Lung function declined 3 months after infection and gradually improved at 6 months, but remained significantly lower compared to pre-COVID-19 values. The more significant decline in FVC than in FEV1 and FEV1/FVC > 70%, suggested a more restrictive pattern.

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COVID-19,SARS-CoV-2,lung transplant,CLAD,transplant function

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