P166. Early Growth Response 1 (EGR1) is Downregulated in Peripheral Blood From Patients With Major Psychiatric Disorders

Bipolar Disorder (BD), Schizophrenia (SZ), and Major Depressive Disorder (MDD) are multifactorial disorders. Thus, should there be interest in genes with the potential to translate environmental stimuli into long-term alterations in the brain, such as Early Growth Response (EGR)1 and EGR3. Day-night cycle may be an important point of environmental and genetic intersection when associated with psychopathology, and Cryptochrome Circadian Regulator 2 (CRY2) is one relevant circadian clock gene.