Ajg-21-0834 2118..2127

Eric D. Shah,Kyle Staller, Judy Nee,Nitin K. Ahuja,Walter W. Chan,Anthony Lembo, Darren M. Brenner, Corey A. Siegel,William D. Chey

semanticscholar

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摘要

METHODS: Weevaluated the subset of patientswith CIC and documented failure of over-the-counter (OTC) osmotic or bulk-forming laxatives. A RAND/UCLA consensus panel of 8 neurogastroenterologists informed model design. Treatment outcomes and costs were defined using integrated analyses of registered clinical trials and the US Centers for Medicare and Medicaid Services–supported cost databases. Quality-adjusted life years (QALYs) were calculated using health utilities derived from clinical trials. A 12-week time horizon was used.

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