Waning antibody levels after vaccination with mRNA BNT162b2 and inactivated CoronaVac COVID-19 vaccines in Hong Kong blood donors
medRxiv(2021)
Abstract
Both inactivated vaccine (CoronaVac; Sinovac) and mRNA vaccine (Comirnaty/BNT162b2; Fosun-Pharma/BioNTech) are available in Hong Kong's COVID-19 Vaccination Programme. We reported waning antibody levels by enzyme-linked immunosorbent assays (ELISA) and surrogate virus neutralization test (sVNT) among 850 fully vaccinated blood donors (i.e., received two doses). The BNT162b2 group's antibody levels remain over the 50% protection threshold within six months, and the CoronaVac's group's median antibody levels begin to fall below the 50% protection threshold two months after vaccination.
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Key words
hong kong blood donors,vaccination,mrna bnt162b2,waning antibody levels
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