Electrosynthesis of CF3‐Substituted Polycyclic Quinazolinones via Cascade Trifluoromethylation/Cyclization of Unactivated Alkene

An atom and step economy cascade trifluoromethylation/cyclization of unactivated alkene with Langlois reagent as a CF3 source is described. A variety of polycyclic quinazolinones were successfully synthesized in 52–81% yields under transition metal‐ and oxidant‐free conditions. The Langlois reagent used in this strategy as a CF3 reagent possesses the advantages of bench‐stablity, cost‐effectivity and high‐efficiency. Additionally, gram‐scale reaction, broad substrate scope and good functional group tolerance demonstrated the synthetic usefulness of this protocol.