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Impact of a Rapid Molecular Test for Klebsiella pneumoniae Carbapenemase and Ceftazidime-Avibactam Use on Outcomes After Bacteremia Caused by Carbapenem-Resistant Enterobacterales.

Michael J Satlin,Liang Chen,Angela Gomez-Simmonds,Jamie Marino,Gregory Weston,Tanaya Bhowmick,Susan K Seo,Steven J Sperber,Angela C Kim,Brandon Eilertson, Sierra Derti,Stephen G Jenkins,Michael H Levi,Melvin P Weinstein,Yi-Wei Tang,Tao Hong,Stefan Juretschko,Katherine L Hoffman,Thomas J Walsh,Lars F Westblade,Anne-Catrin Uhlemann,Barry N Kreiswirth

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2022）

Cited 26|Views44
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Abstract
In a KPC-endemic area, blaKPC PCR testing of positive blood cultures was associated with decreased time until appropriate therapy and decreased mortality for CRE bacteremia, and ceftazidime-avibactam is a reasonable first-line therapy for these infections.
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Key words
Klebsiella pneumoniae carbapenemase,carbapenem-resistant Enterobacterales,ceftazidime-avibactam,rapid diagnostics
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