Severe liver fibrosis in the HCV cure era: Major effects of social vulnerability, diabetes, and unhealthy behaviors

Patrizia Carrieri,Fabrice Carrat,Vincent Di Beo,Marc Bourlière,Tangui Barré,Victor De Ledinghen,Georges-Philippe Pageaux,Morgane Bureau,Carole Cagnot,Céline Dorival,Elisabeth Delarocque-Astagneau,Fabienne Marcellin,Stanislas Pol,Hélène Fontaine,Camelia Protopopescu

JHEP Reports（2022）

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摘要

•Liver fibrosis assessment is a key prognostic tool in the hepatitis C cure era.•Significant liver fibrosis regression does not always occur after hepatitis C cure.•Coffee intake displays protective effects on severe fibrosis even after HCV cure.•Social vulnerability, diabetes, and unhealthy alcohol use predict severe fibrosis.•Socio-behavioral factors are associated with severe fibrosis even after HCV cure.

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关键词

coffee,direct-acting antivirals,FIB-4,hepatitis C,alcohol,social status,diabetes,socio-behavioral factors

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