Classification of disease damage and activity in cutaneous lupus erythematosus: A cross-sectional analysis

To the Editor: Classification of Cutaneous Lupus Disease Area and Severity Index (CLASI) scores provides a framework for disease severity in patients with cutaneous lupus erythematosus (CLE). One prior study classified CLASI activity scores using a small cohort; however, no studies have been performed on CLASI damage (CLASI-D) scores. 1 Klein R. Moghadam-Kia S. LoMonico J. et al. Development of the CLASI as a tool to measure disease severity and responsiveness to therapy in cutaneous lupus erythematosus. Arch Dermatol. 2011; 147: 203-208https://doi.org/10.1001/archdermatol.2010.435 Crossref PubMed Scopus (113) Google Scholar Our objective was to establish CLASI-D strata for mild, moderate, and severe disease using a large, heterogeneous cohort and compare characteristics between categories.