The Relationship Between Tobacco and Cannabis Co-Use in Schizophrenia - Preliminary Studies Using Repetitive Transcranial Magnetic Stimulation (rTMS)

Individuals with schizophrenia (SCZ) have high rates of cannabis and tobacco co-use but the relationships between these substances in SCZ is unknown. In a previous study on cannabis use disorder in schizophrenia versus non-psychiatric controls, we found that 28-days of cannabis abstinence was associated with selective improvements in cognitive function (e.g. verbal and memory) and increased compensatory tobacco use compared to controls. Here, we further explored cannabis and tobacco co-use in SCZ participants undergoing repetitive transcranial magnetic stimulation (rTMS) as a method for reducing cannabis use.