Chlorogenic acid supplementation alleviates dextran sulfate sodium (DSS)-induced colitis via inhibiting inflammatory responses and oxidative stress, improving gut barrier integrity and Nrf-2/HO-1 pathway

Journal of Functional Foods(2021)

Cited 12|Views5
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Abstract
•CGA supplementation can enhance antioxidant capacity in DSS-induced colitis mice.•CGA supplementation can activate Nrf-2/HO-1 pathway in DSS-induced colitis mice.•CGA supplementation can improve gut barrier integrity in DSS-induced colitis mice.
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Key words
Chlorogenic acid,Colitis,Gut barrier,Inflammatory responses,Nrf-2/HO-1
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